Hendawy N. Tawfeek
Minia university, Egypt
Title: Novel synthesis of four scaffolds of quinolone hydrazide hybrid drugs and comparing their biological activities as breast cancer agents
Biography
Biography: Hendawy N. Tawfeek
Abstract
Quinolone and their derivatives have a challenge in their use as prospective pharmacophores in the field of medicinal chemistry. The synthesis of hybrid drug takes the interest of scientists. Here our trend is to synthesize and evaluate the biological activities of four quinolone hydrazide four scaffolds of open structures and heterocycles. The structures of the synthesized compounds were determined by advanced spectroscopic tools as well as X-ray diffraction structure determination.